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KMID : 0361020150580110764
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Korean Journal of Otolaryngology - Head and Neck Surgery
2015 Volume.58 No. 11 p.764 ~ p.768
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Clinical Features and Outcomes of Papillary Thyroid Carcinoma in Patients Aged under 20
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박성호:Park Sung-Ho
최주열:Choi Joo-Yul/김남영:Kim Nam-Young/김경헌:Kim Kyoung-Hun/이국행:Lee Guk-Haeng/이병철:Lee Byeong Cheol/이명철:Lee Myung-Chul/최익준:Choi Ik-Jun
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Abstract
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Background and Objectives: Thyroid carcinoma rarely occurs in children and adolescents, whose clinical features are diverse, and treatment outcomes are still controversial. The aim of this study was to evaluate the clinical features and the treatment outcomes of papillary thyroid carcinoma (PTC) patients younger than 20 years old.
Subjects and Method: This is a retrospective study for patients younger than 20 years old, who were diagnosed as PTC from January 1992 to February 2009. Clinical features, size, pathologic type, extrathyroidal extension, recurrence, multiplicity, extent of surgery, and lymph node metastasis were retrospectively evaluated.
Results: Forty patients, of 6 malse and 34 females, were enrolled, with their mean age being 16 years old. The initial operations were total thyroidectomy for 9 patients, unilateral lobectomy for 15 patients, and total thyroidectomy and lateral neck dissection for 16 patients. Cervical lymph node metastases were diagnosed in 25 patients. Extrathyroidal extensions were observed in 30 patients. Postoperative radioactive iodine therapy was performed in 35 patients. During the follow-up period, 8 patients had recurred. All patients were alive at the last follow-up.
Conclusion: PTC in children and adolescents aged under 20 is a rare disease and tends to present as an advanced disease with low mortality compared to adult PTC. Recurrence had no effect on survival. Aggressive treatment with total thyroidectomy, central neck dissection, and radioiodine therapy may prevent recurrence.
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KEYWORD
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Adolescent, Children, Papillary thyroid carcinoma
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